Programme

The scientific programme will be build around invited lectures from leading scientists, contributed oral presentations chosen among the submitted abstracts and 2 poster sessions (posters list). 

Day 1: Wednesday December 02

09:00 Short course - Statistics analysis for proteomics data

11:00 Registration
14:00 Opening of the Meeting

Session I: Systems Biology (co-organized by SystemsX.ch)

14:15 Introduction by SystemsX.ch representative
14:30 Plenary Lecture: Fotis C. Kafatos (Imperial College, London UK)
Omics for Understanding and Controlling Global Health Diseases (Auditorium maximum)
Auditorium maximum (Systems Biology)
Chair Ruedi Aebersold
Semper Auditorium (Biomedical Applications)
Chair Niels Lion
15:30 Picotti P. (Institute of Molecular Systems Biology, ETH Zurich)
Quantitative targeted proteomics for the analysis of cellular networks
Rösli C. (Institute of Pharmaceutical Sciences, ETH Zurich)
Identification of lymphoma-associated vascular accessible antigens using DeepQuanTR

Vujasinovic T. (helios biosciences, Créteil, France)
Dynamic models of molecular interaction networks to select accurate therapeutic targets
Thaminy S. (Institute of Molecular Systems Biology, ETH Zurich)
Label-free proteomic approach to identify breast cancer biomarkers
16:10 Coffee Break
16:45 Pertz O.C. (Institute for Biochemistry and Genetics, Biomedicine, Basel)
A system biology view of spatio-temporal signaling during polarized cell migration
Kolla V. (University Womens Hospital, Basel)
Quantitative proteomics analysis of maternal plasma in preeclampsia pregnancies using isobaric tagging reagent (iTRAQ)

Bairoch A. (Swiss Institute of Bioinformastics, CALIPHO, Geneva)
CALIPHO: we care about human proteins!
Hüttenhain R. (Institute of Molecular Systems Biology, ETH Zurich)
Protein signatures in plasma for stratification of ovarian cancer subtypes
17:15 Plenary Lecture: Erez Dekel (Weizmann Institute of Science, Rehovot, Israel)
Simplicity in protein dynamic response to drug combinations (Auditorium maximum)
18:15 Apéro and Vendors Event (Bio-Rad/ThermoFischer)

Day 2: Thursday December 03

Session II: Bioinformatics

08:30 Plenary Lecture: Christian von Mering (University of Zürich, Switzerland)
Optimality and evolution of protein abundance levels in eukaryotes
Auditorium maximum (Bioinformatics)
Chair Patricia Palagi
Semper Auditorium (Technology)
Chair Gérard Hopfgartner
09:20 Ahrens C.H. (Center for Model Organism Proteomes, Institute of Molecular Biology, Zurich)
Bioinformatics for systems biology: Directed shotgun proteomics & deterministic protein inference
Tran B.Q. (University of Lausanne, Protein Analysis Facility - Center for Integrative Genomics, Lausanne)
Mapping the trypsin-resistant proteome by targeted multi-enzyme digestion of large tryptic peptides

Nasso S. (University of Padova, Information Engineering, Padova, Italy)
3DSpectra: A Matlab software for easy handling and 3D quantification of LC-MS labeled profile data
Scherl A. (Centre Médical Universitaire, Dept. Struct. Biol. and Bioinformatics, Genève)
Combining low- and high-energy tandem mass spectra for optimized peptide quantification
09:50 Coffee Break  + Poster Session I
11:15 Ferro M. (CEA/Grenoble, Laboratoire EDyP, Grenoble, France)
IRMa and hEIDI : a software duo for the management and the exploration of MS/MS data
Alenas K. (Denator AB, Gothenburg, Sweden)
Heat stabilization of the tissue proteome for improved proteomics

Claassen M. (Institute of Molecular Systems Biology, ETH Zurich)
Proteome coverage prediction for integrated proteomics datasets
McDowall M.A. (Waters Corporation, MS Technology Centre, Manchester, United Kingdom)
Extending the dynamic range of protein quantification and identification with a novel two-dimensional LC/MS approach
11:45 General Assembly SPS
12:45 Lunch

Session III: Biomarkers

13:45 Plenary Lecture: Gérôme Garin (CEA Grenoble, France)
Quantitative Proteomics Applied to Clinical Studies: is there a need to make compromises?
Auditorium maximum (Biomedical Applications)
Chair Hans Voshol
Semper Auditorium (Bioinformatics)
Chair Christine Hoogland
14:30 Wollscheid B. (Institute of Molecular Systems Biology, ETH Zurich)
Phenotyping cells without antibodies - multiplexed analysis of the cell surface information gateway
Grossmann (Functional Genomics Center Zurich, University of Zurich, Zurich)
Evaluation of relative and absolute quantification in shotgun

Surinova S. (Institute of Molecular Systems Biology, ETH Zurich)
Detection of potential colorectal cancer markers in patients’ plasma
Ducret A. (Molecular Medicine Laboratories F. Hoffmann-La Roche AG, Basel)
A novel protein scoring algorithm for shotgun proteomics
15:00 Coffee Break + Poster Session II
16:15 Farina A. (University Medical Center (CMU), Department of Structural Biology and Bioinformatics , Geneva)
Biomarkers identification in malignant biliary stenosis using bile proteomic analysis


Schiess R. (Institute of Molecular Systems Biology, ETH Zurich)
Prostate cancer biomarkers for diagnosis and therapy

16:45-17:45 Plenary Lecture: Dario Neri (ETH Zürich, Switzerland)
Vascular Tumor Targeting: from target discovery to clinical applications
18:45 Apéro
19:15 Conference dinner (ETH Zentrum, Foyer)

Day 3: Friday December 04

Session IV: New trends and technologies in proteomics

08:30-9:20 Plenary lecture: Ron Heeren (AMOLF, Amsterdam, The Netherlands)
Imaging mass spectrometry of biological surfaces: innovation in biomolecular imaging
Auditorium maximum (Technology)
Chair Michael Affolter
Semper Auditorium (Systems Biology)
Chair Amos Bairoch
09:30 Schmidt A. (Institute of Molecular Systems Biology, ETH Zurich)
Proteome-wide high-throughput screening using directed mass spectrometry: Application to the human pathogen L. interrogans
Trinh H.V. (Institute of Molecular Biology, University of Zurich, Zurich)
Functional genomics approaches to study molecular system dynamics of human adenovirus infection

Altelaar M. (Utrecht University, Biomolecular Mass Spectrometry and Proteomics Group, Utrecht, The Netherlands)
Database independent proteomics; de novo sequence analysis by a combination of LysN protein digestion and electron transfer dissociation
Rutishauser D. (Functional Genomics Center Zurich, University and ETH, Zurich)
Quantitative analysis of adipose and liver tissue of obese mice using LTQ Orbitrap XL

Scheffler K. (Thermo Fisher Scientific, Dreieich, Germany)
Maximizing protein ID by minimizing cycle time
Schauer M.A. (Institute of Plant Biology, Zurich/CH)
Protein dynamics during arabidopsis male gametophyte development

Matondo M. (Institute of Molecular Systems Biology, ETH Zurich)
Qualitative screening of urinary biomarkers by selected reaction monitoring
Weisser H. (Institute of Molecular Systems Biology, ETH Zurich)
A hybrid strategy for LC-MS-based quantitative proteomics
10:30
Coffee Break
11:15 Plenary lecture: Gérard Hopfgartner (University of Geneva, Switzerland)
Strategies to improve MRM selectivity and alternative approaches for proteins and peptides quantitation
12:00 Plenary lecture: Pierre Thibault(University of Montreal, Canada)
Evolution of phagocytosis functions revealed through the proteomics lens
12:50 Closing remarks

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